Wednesday, October 21, 2009

is any1 having/familiar with Parkinson's disease?


Answers:
Parkinson's disease (also known as PD or Parkinson Disease) is a degenerative disorder of the central nervous system, that affects the control of muscles, and so may affect movement, speech and posture. Parkinson's disease belongs to a group of conditions called movement disorders. It is often characterized by muscle rigidity, tremor, a slowing of physical movement (bradykinesia), and in extreme cases, a loss of physical movement (akinesia). The primary symptoms are due to excessive muscle contraction, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain.PD is both chronic, meaning it persists over a long period of time, and progressive, meaning its symptoms grow worse over time. It is not contagious. Although some PD cases appear to be hereditary, and a few can be traced to specific genetic mutations, most cases are sporadic 鈥?that is, the disease does not seem to run in families. Many researchers now believe that PD results from a combination of genetic susceptibility and exposure to one or more environmental factors that trigger the disease.PD is the most common form of parkinsonism, the name for a group of disorders with similar features and symptoms. PD is also called primary parkinsonism or idiopathic PD. The term idiopathic means a disorder for which no cause has yet been found. While most forms of parkinsonism are idiopathic, there are some cases where the cause is known or suspected or where the symptoms result from another disorder. For example, parkinsonism may result from changes in the brain's blood vessels.
What emman said. Just wanted to add, that my paternal grandmother had parkinsons before she died, my father has parkinsons and I believe that I am showing signs of parkinsons, so there can be some truth to it running in families. Not a very nice thing to live through, thats for sure.
Parkinsons disease is some times deadly, i know a close relative of mine died of this disease. U see the charactersitic muscle rigidity due to an abnormality in dopamine metabolism, which is a biological molecule produced from an aminoacid tyrosine.
I know u dont have much time to read lengthy answers so im just giving u a brief answer.PD is rigidity of muscles due to brain stem lesion and it is caused by decreased formation of dopamin.But it is not always fatal for life cuz when my grandmother was 40 she got this disease and she died at a normal age of 90.

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