Wednesday, October 21, 2009

is carcinoma polyclonal or monoclonal?

Malignancies in general, including epithelial malignancies (carcinomas) usually arise from a single cell that has mutated and then procedes to start dividing out of control. Therefore malignant tumors in general are typically monoclonal.
Depends on the tissue and type.
from the degeneration of the cell its monoclonal, but when this one produces other cells is polyclonal.
the primary engine is the degeneration of a stem cell, this has the ability to differentiated and undifferentiated, thus producing more degenerate cells.

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